yxjB [2017-8-11 16:0:3]

unknown

locus: BSU39010

pI: 8.13

mw: 31.32 kDa

protein length: 282 aa

gene length: 846 bp

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]

Gene

Coordinates: 4,004,288 → 4,005,136

Expression and Regulation

Operons

• genes: [gene|65253C69BAE9679FE4475BFF76BBABBB0FA70C30|tlrB]
  description: [Pubmed|10746760]

  regulatory mechanism

  • [protein|4910F1E5BAF274C828FD92C410A1B86FB1D358CE|TlrBL]: attenuation, [pubmed|31719185], in [regulon|4910F1E5BAF274C828FD92C410A1B86FB1D358CE|TlrBL regulon]

  regulation

  • induced in the presence of tylosin (transcription attenuation and translation attenuation in the absence of tylosin) [Pubmed|31719185]
  • induction depends on [protein|43CFA3477B4EEB4CE0B2DF63ED2B5EDB171E79C7|NusG]-dependent [SW|RNA polymerase] pausing between the leader peptide [protein|4910F1E5BAF274C828FD92C410A1B86FB1D358CE|TlrBL] and [gene|65253C69BAE9679FE4475BFF76BBABBB0FA70C30|tlrB] coding sequences [Pubmed|31719185]

  additional information

  • a [protein|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|NusA]-dependent terminator and an SD-sequestering hairpin are present in the [gene|65253C69BAE9679FE4475BFF76BBABBB0FA70C30|tlrB] leader [Pubmed|31719185,27120414]

Biological materials

Mutant

• MGNA-B726 (yxjB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1725 NBRP B. subtilis, Japan]
• 1A995 ( ''yxjB''::''spec''), [Pubmed| ], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A995&Search=1A995 BGSC]

References

• 10746760,27120414